Silibinin releasing mesoporous bioactive glass nanoparticles: potential for breast cancer therapy

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Our paper “Silibinin releasing mesoporous bioactive glass nanoparticles with potential for breast cancer therapy” has been published on-line in Ceramics International  [1]. In collaboration with Dr. Aldo Leal-Egana, we investigated a novel combination of mesoporous bioactive glass nanoparticles (mean size: 120 ± 10 nm) as a carrier and release system for silibinin, a natural flavonolignan used as anticancer agent. The effect of silibinin was tested on metastatic MDA-MB-231 breast cells and on non-metastatic breast cell line MCF-10A.

[1] Q. Nawaz et al., Silibinin releasing mesoporous bioactive glass nanoparticles with potential for breast cancer therapy,Ceram. Int. (2020) in press.