Influence of the incorporation of metallic ions in bioactive glass-scaffolds
Supervisors: Marcela Arango-Ospina, Prof. Dr.-Ing. habil. Aldo R. Boccaccini
Bioactive glasses (BGs) are widely considered for bone tissue engineering applications due to their bioactive behavior. Formed as scaffolds, they are able to imitate the natural porous structure required for bone-application . There are a number of different metallic ions which can be incorporated in BGs, e.g. boron, magnesium and zinc are used to provide additional properties such as osteogenesis, angiogenesis or to enhance bioactivity, e.g. boron stimulates RNA synthesis in fibroblast cells. In this project, the incorporation of metallic ions in the silicate-based BG ICIE16  is analyzed. The aim of this bachelor thesis is to investigate the influence of the ions in the processing of scaffolds and their bioactive behavior. For this research process the classical foam replica technique introduced in 2006 to produce BG scaffolds is used  .The samples will be characterized with scanning electron microscopy (SEM), FTIR and the mechanical properties will be measured.
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