Dr. Elif Yüce Eroğlu

TÜBİTAK 2219 Postdoctoral Research Fellow, Visiting researcher from Türkiye

Lung Tissue Engineering with Advanced Bioinks and Biofabrication

Supervisor: Prof. Dr.-Ing. habil. Dr. h.c. Aldo R. Boccaccini

Three-dimensional (3D) bioprinting offers the possibility of fabricating patient-specific scaffolds with controlled architecture and biofunctionality. High Internal Phase Emulsions (HIPEs) have emerged as promising candidates for developing bioinks due to their ability to generate hierarchical porosity and tunable mechanical properties [1,2]. This project focuses on the development of novel bioinks for 3D bioprinting. By incorporating bioactive glasses and essential oils, the bioinks are designed to provide interconnected hierarchical porosity, controlled ion release, and antibacterial/antioxidant properties. The ultimate aim is to fabricate patient-specific lung tissue scaffolds and explore their regenerative potential using advanced characterization and machine learning approaches. The research is supported by the Scientific and Technological Research Council of Türkiye (TÜBİTAK).

[1] Kramer, S., Cameron, N.R., Krajnc, P. (2021). Porous Polymers from High Internal Phase Emulsions as Scaffolds for Biological Applications. Polymers, 13, 1786.

[2] Yüce, E., Krajnc, P., Mert, H.H., Mert, E.H. (2019). Influence of Nanoparticles and Antioxidants on Mechanical Properties of Titania/Polydicyclopentadiene PolyHIPEs: A Statistical Approach. Journal of Applied Polymer Science 136, 46913.