Dr. Patrycja Domalik-Pyzik

Visiting researcher (AGH University of Krakow, Poland)

Engineering Vascularized Implants for Personalised Osteochondral Tissue Regeneration: From medical imaging to pre-clinical validation

Collaborators: Andrada-Ioana Damian-Buda, Dulce Medina Bueno, Prof. Aldo R. Boccaccini

Within the European MSCA EngVIPO project ( https://engvipo.i3bs.eu/ ), this secondment focused on extrusion-based 3D printing of alginate dialdehyde–gelatin (ADA–GEL) composite hydrogels, enriched with bacterial cellulose and modified with tricalcium phosphate (TCP) for osteochondral scaffold development. The work involves bioink preparation, ceramic dispersion, systematic optimization of printing parameters, and comparison of scaffold geometries at increasing mineral content. This project will confirm a processing window for ADA–GEL/TCP systems and will increase the methodological cooperation between the Institute of Biomaterials at FAU Erlangen-Nuremberg and AGH University of Krakow, Faculty of Materials Science and Ceramics, Department of Biomaterials and Composites, toward future biofabricated osteochondral constructs.
The EngVIPO project (https://engvipo.i3bs.eu/ ) has received funding from the European Union’s Horizon Europe programme (HORIZON-MSCA-2023-SE-01-01) under Grant Agreement No. 101183041.