Jaime Orellana

Jaime Orellana

Visiting PhD student (Polytechnic University of Madrid, Spain)

Cell viability on PLA-Mg scaffolds for bone tissue regeneration


Supervisor in Spain: Prof Dr. José Ygnacio Pastor (Polytechnic University of Madrid, Madrid, Spain)

Collaborators: Prof Dr. Begoña Ferrari (Institute of Glass and Ceramic, Madrid, Spain); Dr Ana Ferrández-Montero (University of Cergy, Paris, France)

Supervisors in Erlangen: Prof. Dr. Aldo R. Boccaccini, Dr. Rainer Detsch

This project is framed into the Doctoral Thesis dealing with thermal, mechanical and biological properties of novel PLA-Mg materials for additive manufacturing. PLA scaffolds can be used for the regeration of bone tissues. However, bone tissue regeneration is a slow process. Adding Mg microparticles into the PLA composition enhances bone regeneration, as studied by Ferrandez-Montero et al. [1,2]. On the light of previous results related to the cell viability on PLA/Mg films, the present study at the FAU Institute of Biomaterioals will investigate in deeper detail the cell viability on 3D printed PLA-Mg scaffolds.

[1] Ferrández-Montero, A.; Lieblich, M.; Benavente, R.; González-Carrasco, J.L.; Ferrari, B. Study of the matrix-filler interface in PLA/Mg composites manufactured by Material Extrusion using a colloidal feedstock. Addit. Manuf. 2020, 33, 101142.

[2] Ferrández-Montero, A.; Lieblich, M.; González-Carrasco, J.L.; Benavente, R.; Lorenzo, V.; Detsch, R.; Boccaccini, A.R.; Ferrari, B. Development of biocompatible and fully bioabsorbable PLA/Mg films for tissue regeneration applications. Acta Biomater. 2019, 98, 114-124.