Electrofabrication of chitosan films/ porous patches for biomedical applications
Supervisor: Muhammad Asim Akhtar and Prof. Aldo R. Boccaccini
Chitosan is a well-known natural biopolymer. This polysaccharide is a promising candidate for different biomedical applications due to its biodegradability, intrinsic antibacterial and cytocompatible nature . Electrophoretic deposition (EPD) is a versatile and widely used process that can be carried out at room temperature . In this study the EPD process will be used to manufacture chitosan based free-standing porous patches modified with therapeutic ions and phytotherapeutic agents. A recent study found increased antibacterial activity and improved mechanical properties of copper(II)-chitosan complex based coatings obtained by EPD . The characterization of the fabricated 3D shapes will take part in this study.
 J. M. Vaz, et al., Antibacterial Coatings Based on Chitosan for Pharmaceutical and Biomedical Applications, Current Pharmaceutical Design, 2018, 24, 866-885
 E. Avcu, et al., Electrophoretic deposition of chitosan-based composite coatings for biomedical applications: A review. Prog. Mater. Sci.2019,103,69–108.
 M. A. Akhtar et al., Electrophoretic Deposition of Copper(II)–Chitosan Complexes for Antibacterial Coatings, Int. J. Mol. Sci. 2020, 21, 2637.