Former visiting student (Warsaw University of Technology, Poland)
Zein particles as drug delivery systems
Supervisors: Zoya Hadzhieva, Prof. Dr.-Ing. habil. Aldo R. Boccaccini
There is a growing need for developing new drug carriers for drug delivery applications. One such carrier might be drug-loaded polymeric particles, in which the drug is encapsulated in a hydrophobic polymeric matrix that serves as a drug carrier . Among many materials used as drug carriers biopolymers draw attention, thanks to their biocompatibility and biodegradability . One such polymer is zein – a hydrophobic protein derived from corn. Different molecules obtained from natural resources such as green tea and coffee are being considered as phytotherapeutic agents. Some natural compounds exhibit anti-cancer properties . In this study, zein particles loaded with natural drugs are being manufactured. The obtained drug delivery systems are tested for their colloidal stability, drug encapsulation efficiency and particle size.
 L. I. Atanase, ‘Micellar Drug Delivery Systems Based on Natural Biopolymers’, Polymers, vol. 13, no. 3, p. 477, Feb. 2021, doi: 10.3390/polym13030477.
 R. A. Youness, R. Kamel, N. A. Elkasabgy, P. Shao, and M. A. Farag, ‘Recent Advances in Tannic Acid (Gallotannin) Anticancer Activities and Drug Delivery Systems for Efficacy Improvement; A Comprehensive Review’, Molecules, vol. 26, no. 5, Art. no. 5, Jan. 2021, doi: 10.3390/molecules26051486.