Laura de Lara
Visiting researcher, University of Granada, Spain
Development of bioinks combining alginate dialdehyde (ADA) and biological molecules for osteochondral tissue regeneration
Collaborator: Prof. Aldo R. Boccaccini
This research stay is being conducted within the framework of the EngVIPO project [1], in which the University of Granada (UGR) and the Institute of Biomaterials at Friedrich-Alexander University Erlangen-Nürnberg (FAU) collaborate alongside other international partner institutions to develop novel biomaterials and biofabricated patient-specific implants for osteochondral regeneration.
Specifically, during this research stay, the project will focus on the development of bioinks combining Alginate dialdehyde (ADA), a biomaterial optimized for osteochondral regeneration, with decellularized extracellular matrix (dECM) derived from Mesenchymal Stem Cells [2]. The incorporation of dECM provides a biomimetic, highly regenerative, and patient-derived microenvironment, enabling the development of personalized therapeutic approaches.
[2] Antich C, et al. (2021). Development of a Biomimetic Hydrogel Based on Predifferentiated Mesenchymal Stem Cell-Derived ECM for Cartilage Tissue Engineering. Advanced Healthcare Materials, 10(8), e2001847. https://doi.org/10.1002/adhm.202001847