Drug-free antibacterial polyesters for the treatment of infections
Betreuer: Prof. Dr.-Ing. habil. Aldo R. Boccaccini, Dr. Chris Lovell (Lucideon, UK)
Set within the European-funded European Industrial Doctorates (EID) network “Drug-Free Antibacterial Hybrid Biopolymers for Medical Applications” (HyMedPoly) (Horizon 2020), this project aims to investigate new strategies for the development of therapies based on biomedical drug-free antibacterial polyesters for the treatment of infections. The research will focus on designing biodegradable and bioresorbable polyesters exploiting the antibacterial potential of the hydrolytic degradation of the polyesters itself. The coupling of these materials with other antibacterial agents will be also investigated. The new material will be fully characterized in terms of physico-chemical properties, antibacterial activity and biological compatibility in order to assess its suitability for soft tissue engineering and/or wound healing applications. The project involves strong collaboration with the industrial partner (Lucideon Ltd.), UK, where part of the research activities will be carried out.
Polycaprolactone Electrospun Fiber Mats Prepared Using Benign Solvents: Blending with Copper(II)-Chitosan Increases the Secretion of Vascular Endothelial Growth Factor in a Bone Marrow Stromal Cell Line
In: Macromolecular Bioscience (2020), Article No.: 1900355
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Polylactide-based materials science strategies to improve tissue-material interface without the use of growth factors or other biological molecules.
In: Materials Science and Engineering C 94 (2019), p. 1083-1101
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An investigation on antibiotic-free antibacterial materials combining bioresorbable polyesters, chitosan and therapeutic ions (Dissertation, 2019)
Synthesis and characterization of silver-doped mesoporous bioactive glass and its applications in conjunction with electrospinning
In: Materials 11 (2018), Article No.: 692
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Fabrication and characterization of copper(II)-chitosan complexes as antibiotic-free antibacterial biomaterial
In: Carbohydrate Polymers 179 (2018), p. 370-378
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Do bioresorbable polyesters have antimicrobial properties?
In: Journal of Materials Science: Materials in Medicine 29 (2018), Article No.: 18
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Nanostructured biocomposites for tissue engineering scaffolds
In: Prof Luigi Ambrosio (ed.): Biomedical Composites, 2nd Edition, Cambridge, UK: Woodhead Publishing, 2017, p. 501-542
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