Shadi Noorani

Master student

Organic-Inorganic Coatings Using Electrophoretic Deposition (EPD)

Supervisors: Luis Guilherme Silva Rosa, Prof. Aldo R. Boccaccini

This project investigates the fabrication of organic–inorganic composite coatings composed of gelatin/chitosan matrices incorporating ion doped mesoporous bioactive glass nanoparticles using electrophoretic deposition (EPD), a versatile technique for producing uniform and functional biomedical coatings [1]. The gelatin–chitosan matrix provides a biocompatible and positively charged system suitable for EPD; gelatin enhances hydrophilicity and film-forming properties, while chitosan contributes charge density and inherent antimicrobial functionality. MBGns further introduce controlled ion release, enhanced osteogenic potential, and antibacterial effects. The study examines suspension stability, deposition behavior, coating, adhesion, morphology, wettability, and the bioactivity and cytocompatibility of the hybrid coatings. Building on recent advances in EPD-based antibacterial and bioactive surface modification strategies [2], this work aims to establish ion doped MBGn/chitosan/gelatin hybrid films as multifunctional coatings for improved implant integration.

[1] Boccaccini, A. R. et al., Electrophoretic deposition of biomaterials, J. R. Soc. Interface, 2010. https://doi.org/10.1098/rsif.2010.0156.focus

[2] Hadzhieva, Z., Boccaccini, A. R., Recent developments in EPD of antibacterial coatings for biomedical applications, Review. https://doi.org/10.1016/j.cobme.2021.100367