Visiting PhD student (Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, China)
Development of hybrid and composite hydrogels based on the bioactive glass for bone tissue regeneration
Supervisors: Dr. Kai Zheng, Prof. Aldo R. Boccaccini
Hybrid or multimaterial hydrogels with organic and inorganic components are promising materials commonly used to promote bone regeneration . However, the wide application of composite materials may be compromised if they exhibit poor interfacial compatibility . Modifying organic or inorganic components can improve interfacial compatibility and consequently enhance the properties of hybrid hydrogels . In this project, hybrid and composite hydrogels based on bioactive glasses (BGs) and natural polymers (e.g., ADA-GEL, chitosan) will be developed following previous approaches  established in our Institute. In-depth physiochemical characterization and biological tests will be performed. Optimal components of hybrid (or composite) hybrogels will be selected to promote bone tissue regeneration.
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 A. Leite, et al., Bioplotting of a bioactive alginate dialdehyde-gelatin composite hydrogel containing bioactive glass nanoparticles. Biofabrication 8, 035005 (2016).