Electrophoretic deposition and characterization of functional coatings based on chitosan-metal composites
Betreuer: Muhammad Asim Akhtar, Prof. Dr.-Ing. habil. Aldo Boccaccini
The natural polymer chitosan has a great potential in a broad spectrum of biomedical applications due to its appealing intrinsic physical and biological characteristics . One key feature of chitosan is its ability to form complexes with a wide range of metal ions, in particular transition elements. As reported recently, the incorporation of metallic ions as therapeutic agents in a chitosan matrix shows promising results, regarding antibacterial, antifungal and cytocompatible performance . Moreover chitosan can be combined with metallic nanoparticles (e.g. Ag) to form antibacterial coatings . Therefore, the aim of the current work is the preparation of functional coatings, based on chitosan incorporating metallic inclusions by electrophoretic deposition . The optimized coating materials will be fully characterized in terms of physico-chemical properties, antibacterial activity and in vitro cell viability, in order to evaluate their suitability for bone tissue engineering and orthopedic applications.
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