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Our last paper on oxidized alginate-gelatin hydrogel published

 

Our paper entitled: “Oxidized Alginate-Gelatin Hydrogel: A Favorable Matrix for Growth and Osteogenic Differentiation of Adipose-Derived StemvCells in 3D”, co-authors: B Sarker, T Zehnder, SN Rath, RE Horch, U Kneser, R Detsch, A. R. Boccaccini, has been publIshed in ACS Biomaterials Science & Engineering (Sarker et al., ACS Biomater. Sci. Eng., 2017, 3 (8), pp 1730–1737). The study was carried out in collaboration with colleagues at the Department of Plastic and Hand Surgery, University of Erlangen-Nuremberg, the Department of Hand, Plastic, and Reconstructive Surgery, Burn Center, BG Trauma Center Ludwigshafen and the Department of Plastic and Hand Surgery, University of Heidelberg, Heidelberg, Germany. In this paper [1] we continued our investigation of the oxidized alginate-gelatin hydrogel system, developed for the first time in the framework of B. Sarker’s doctoral thesis in 2014 [2], demonstrating the application of covalently cross-linked oxidized alginate-gelatin hydrogels to encapsulate human adipose-derived stem cells. The effect of different hydrogel compositions on stem cell behavior in 3D was investigated. The favourable cell behaviour confirmed the suitability of the hydrogel system for cell encapsulation and bone tissue engineering applications.

[1] B. Sarker, et al., Oxidized Alginate-Gelatin Hydrogel: A Favorable Matrix for Growth and Osteogenic Differentiation of Adipose-Derived Stem
Cells in 3D, ACS Biomaterials Science & Engineering, ACS Biomater. Sci. Eng., 2017, 3 (8), 1730–1737.

[2] B. Sarker, et al., Fabrication of alginate–gelatin crosslinked hydrogel microcapsules and evaluation of the microstructure and physico-chemical properties,
J. Mater. Chem. B 2014, 2, 1470-1482.

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