Our article “Re-engineering Artificial Neoplastic Milieus: Taking Lessons from Mechano and Topobiology” published in: Trends in Biotechnology.
Our article “Re-engineering Artificial Neoplastic Milieus: Taking Lessons from Mechano and Topobiology”, authored by Dr. Aldo Leal-Egaña, Prof. Martial Balland and Prof. Aldo R. Boccaccini has been recently published in the Journal Trends in Biotechnology [1]. In this review, we describe recent advances in designing and performing polymer-based matrices mimicking tumoral tissues, based on current findings in mechano- and topobiology. From bare 2D surfaces to 3D and 1D microstructured platforms, our article discusses current limitations of tissue engineering approaches, suggesting how the biofabrication of tumor-like scaffolds may be improved by taking lessons from the study of cell mechano- and toposensing.
[1] A. Leal-Egaña, et al., Re-engineering Artificial Neoplastic Milieus: Taking Lessons from Mechano and Topobiology” published in: Trends in Biotechnology (2019) in press.