Our recent Biomaterials paper on bioactive glass interaction with giant cell tumor of bone featured in the Bulletin of the American Ceramic Society

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The article “Bioactive glass demonstrates potential in treating giant cell tumor of bone”, published in  the September 2021 issue of Ceramic Bulletin, the Bulletin of the American Ceramic Society, features our recent scientic publication in Biomaterials: “Selective and caspase-independent cytotoxicity of bioactive glasses towards giant cell tumor of bone derived neoplastic stromal cells but not to bone marrow derived stromal cells” (DOI: 10.1016/j.biomaterials.2021.120977). The cell biology based study, carried out in collaboration with Dr. Jörg Fellenberg and  Dr. Fabian Westhauser, at the Center for Orthopedics, Trauma Surgery, and Spinal Cord Injury at Heidelberg University Hospital, showed that different bioactive glass compositions were capable of inducing a significant decrease of neoplastic stromal cell viability, while the viability of regular mesenchymal stromal cells was not affected when exposed to the bioactive glasses. The research is funded by a grant from German Cancer Aid (Deutsche Krebshilfe).