Our recent Biomaterials paper on bioactive glass interaction with giant cell tumor of bone derived neoplastic stromal cells featured in Ceramic Tech Today

Veröffentlichung Beitragsbild

The article “Minimize recurrence, maximize regeneration—bioactive glass demonstrates potential in treating giant cell tumor of bone”  by Lisa McDonald published on 17th July in Ceramic Tech Today, the online news platform of the American Ceramic Society, features our recent scientic publication in Biomaterials: “Selective and caspase-independent cytotoxicity of bioactive glasses towards giant cell tumor of bone derived neoplastic stromal cells but not to bone marrow derived stromal cells” (DOI: 10.1016/j.biomaterials.2021.120977). In this in vitro study, in collaboration with Dr. Jörg Fellenberg and Dr. Fabian Westhauser, at the Center for Orthopedics, Trauma Surgery, and Spinal Cord Injury at Heidelberg University Hospital, we showed that different bioactive glasses induced a significant decrease of neoplastic stromal cell viability, while the viability of regular mesenchymal stromal cells was not affected when exposed to the bioactive glasses. The research is funded by a grant from German Cancer Aid (Deutsche Krebshilfe).